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Effect of femoral nerve block combined with general anesthesia on cognitive dysfunction after PFNA in elderly patients

Effect of femoral nerve block combined with general anesthesia on cognitive dysfunction after PFNA in elderly patients

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100047206
Enrollment
Unknown
Registered
2021-06-10
Start date
2021-06-16
Completion date
Unknown
Last updated
2022-01-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Femoral fractures

Interventions

Experimental group:Femoral nerve block

Sponsors

Affiliated Hospital of Traditional Chinese Medicine of Southwest Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 95 Years

Inclusion criteria

Inclusion criteria: 1. PFNA should be performed in accordance with the diagnosis of femoral fracture; 2. If the patient is over 65 years old (including 65 years old), follow the consent of the patient and his/her family; 3. Signed the informed consent and accepted the experimental treatment voluntarily as the subject.

Exclusion criteria

Exclusion criteria: 1. Unable to cooperate with others, with a history of dementia, mental development disorder, cerebral infarction, myocardial infarction, depression, bleeding and coagulation disorders; 3. Participating in other clinical trials or within 12 weeks prior to the trial; 4. Those who need to change to other treatment methods due to their illness; 5. Others who, at the discretion of the Investigator, are not eligible to participate in the clinical trial.

Design outcomes

Primary

MeasureTime frame
Mini-Mental State Examination;

Secondary

MeasureTime frame
Tumor Necrosis Factor Alpha;Interleukin 1;Serotonin;Prostaglandin E2;ß-endorphin;S-100ß protein;

Countries

China

Contacts

Public ContactJiang Ping

Affiliated Hospital of Traditional Chinese Medicine of Southwest Medical University

850888062@qq.com+86 8303151687

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026