alcohol dependence
Conditions
Interventions
Case series:No
Sponsors
Peking University Sixth Hospital
Eligibility
Sex/Gender
Male
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Meet the DSM-iv diagnostic criteria for alcohol dependence; 2. Aged 18 to 60 years; 3. Han nationality; 4. Male; 5. CIWA-Ar score <11 points; 6. Can complete related scale evaluation; 7. The education level is junior high school and above.
Exclusion criteria
Exclusion criteria: 1. Patients who additionally suffered from other Axis I psychiatric disorders according to DSM-iv and any previous or current substance dependence other than nicotine use according to DSM-iv; 2. Significant underlying medical conditions (e.g., cardiovascular or cerebrovascular disease); 3. Receive any pharmacological treatment altering alcohol craving, such as acamprosate, aripiprazole, quetiapine, baclofen or nalmefene; 4. Those who are claustrophobic or have metal implants may not be suitable for MRI testing 5. Informed consent cannot be signed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wsiconsin card sorting test ,WCST;Barratt Impulse Scale 11th Edition;Monetary Choice questionnaire, MCQ;genetic testing;Functional magnetic resonance;Diffusion tensor imaging; | — |
Secondary
| Measure | Time frame |
|---|---|
| Michigan Alcoholism Screening Test, MAST;Alcohol Urge Questionnaire, AUQ;Visual Analog Scale, VAS;Concise mental status check; | — |
Countries
China
Contacts
Public ContactSun Hongqiang
Peking University Sixth Hospital
Outcome results
None listed