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Nervo-endocrine-immune mechanism of Shaoyao-Gancao decoction for the treatment of liver stagnation and spleen deficiency type alopecia areata by regulating the HPA axis

Nervo-endocrine-immune mechanism of Shaoyao-Gancao decoction for the treatment of liver stagnation and spleen deficiency type alopecia areata by regulating the HPA axis

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100047194
Enrollment
Unknown
Registered
2021-06-10
Start date
2021-06-10
Completion date
Unknown
Last updated
2022-01-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alopecia Areata

Interventions

Sponsors

China-Japan Friendship Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 60 years, gender: male or female; 2. Meet the diagnostic criteria of alopecia areata in Chinese Clinical Dermatology and the diagnostic criteria of liver stagnation and spleen deficiency type in Chinese Medicine Diagnostics; 3. Severity of alopecia areata can be assessed as S2 or S3 with reference to the criteria established by the American Baldness Association guidelines; 4. Patients that can adhere to the medication and follow-up and sign informed consent; 5. Without systemic treatment for hair loss within 3 months and topical treatment for hair loss within 1 month; 6. Without serious liver or kidney dysfunction and water-electrolyte disorders.

Exclusion criteria

Exclusion criteria: 1. Patients with severe heart, liver and kidney diseases and psychiatric disorders; 2. Allergic or contraindicated to Shaoyao-Gancao Decoction; 3. Participated in other clinical trials in the last 3 months; 4. Any other condition that the investigator considers unsuitable for participation in the trial.

Design outcomes

Primary

MeasureTime frame
Severity of Alopecia Tool;

Secondary

MeasureTime frame
Hair microscopy image analysis;

Countries

China

Contacts

Public ContactYang Dingquan

China-Japan Friendship Hospital

ydqlx@163.com+86 13901218671

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026