Induced abortion
Conditions
Interventions
Experimental groupA:Fentanyl + propofol
Experimental groupB:Esketamine + propofol
Experimental groupC:Fentanyl + Remazolam
Experimental groupD:Esketamine + Remazolam
Sponsors
Affiliated Hospital of Guizhou Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 45 years; ASA i- ii; BMI 18-28 kg /m^2; 2. Patients receiving painless abortion in the outpatient department; 3. Clearly understand and voluntarily participate in the study, and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with obvious respiratory and circulatory dysfunction, abnormal blood routine and blood biochemical indexes before surgery; 2. Suffering from severe neuropsychiatric diseases; 3. People suffering from infectious diseases; 4. Taking benzodiazepines or opioids intermittently every day for 1 month or for nearly 3 months; 5. Allergies or contrains to benzodiazepines, opioids, propofol and other drugs and their drug components; 6. Patients judged to have difficulty in airway management: modified Markov score iii or above; 7. Patients participating in other clinical trials; 8. Patients considered by the investigator to be inappropriate to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vital signs change;Induction time of anesthesia;Wake up of time;Departure standard time;Incidence of depression; | — |
Countries
China
Contacts
Public ContactChen Jiejuan
Affiliated Hospital of Guizhou Medical University
Outcome results
None listed