Subclinical hypothyroidism during pregnancy
Conditions
Interventions
TPOAb positive subclinical hypothyroidism during pregnancy:No
TPOAb negative subclinical hypothyroidism during pregnancy:No
Sponsors
Beijing Obstetrics and Gynecology Hospital, Capital Medical University
Eligibility
Sex/Gender
Female
Age
25 Years to 51 Years
Inclusion criteria
Inclusion criteria: 1. Pregnant women of 6-13+6 weeks; 2. Single pregnancy; 3. Subclinical hypothyroidism during pregnancy was diagnosed in our hospital according to thyroid function screening in early pregnancy; 4. Signing the informed consent.
Exclusion criteria
Exclusion criteria: 1. Pregnancy outcome follow-up was not possible; 2. Withdrawal from the project during follow-up; 3. People with other systemic serious autoimmune diseases; 4. Patients with serious diseases of heart, liver, kidney, lung and other important organs; 5. People who adjusted the daily dose of LT4 tablets randomly; 6. Those who failed to complete fecal sample collection of the second trimester due to abortion or loss of follow-up; 7. Drug history of affecting thyroid function; 8. Life history of endemic goiter disease area; 9. History of mental illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TSH;FT4;TPOAb;Delivery gestational age; | — |
Countries
China
Contacts
Public ContactYin Chenghong
Beijing Obstetrics and Gynecology Hospital, Capital Medical University
Outcome results
None listed