Multisystem atrophy, Parkinson's disease
Conditions
Interventions
Sponsors
Dongfang Hospital of Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. According to the diagnosis of PD and MSA, the patients aged 30 to 80 years; 2. All the included cases were selected as mild and moderate patients; 3. According to Hoya classification (HY), the patients with HY 3 were selected as PD patients, and the PD evaluation time was selected as the opening time, 1.5-3 hours after taking medicine; 4. According to the unified multiple system atrophy assessment scale (UMSARS-IV), the patients with UMSARS-IV <=3 were selected as MSA patients Patients in the hospital.
Exclusion criteria
Exclusion criteria: 1. Nervous system examination showed that there were brain atrophy or dementia caused by systemic diseases or other clear reasons, such as severe depression, cerebrovascular disease, poisoning and metabolic diseases; 2. Obvious slowing down of vertical rapid scanning or vertical supranuclear gaze paralysis; 3. Evidence of local cerebral cortex damage, such as aphasia, allopathy, parietal lobe dysfunction; pregnant women, with severe heart, liver and kidney diseases that who can not complete the scale and related examinations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| DTI, fMRI (BOLD);unified Parkinson disease rating scale, UPDRS-U-3;Hoehn-Yahr (H-Y) staging score;NMSS;TCM Syndrome Scale of Kidney Deficiency and Pulp Reduction;UMSARS-I, II;MSA-NMSS; | — |
Countries
China
Contacts
Public ContactChen Zhigang
Beijing University of Chinese Medicine
Outcome results
None listed