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Prospective study of the relationship between postoperative acute pain and COMT gene polymorphism and molecular mechanism in patients with gastric cancer

Prospective study of the relationship between postoperative acute pain and COMT gene polymorphism and molecular mechanism in patients with gastric cancer

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100047161
Enrollment
Unknown
Registered
2021-06-09
Start date
2021-06-01
Completion date
Unknown
Last updated
2022-01-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cancer,pain

Interventions

case group:Nil

Sponsors

Department of Anesthesiology, Peking University Cancer Hospital & Institute
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 79 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged from 18 to 80 years; 2. ASA grade I-III; 3. Pathological diagnosis of malignant tumors, patients undergoing radical cancer surgery.

Exclusion criteria

Exclusion criteria: 1. Patient tumor recurrence; 2. Other parts of the combined primary malignancies; 3. Patients receiving long-term psychotropic and analgesic medications; 4. Schizophrenia, epilepsy preoperative; 5. History of chronic pain; 6. Severe liver and kidney dysfunction.

Design outcomes

Primary

MeasureTime frame
Pain score;

Countries

China

Contacts

Public ContactTan Hongyu

Key laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Anesthesiology, Peking University Cancer Hospital & Institute

maggitan@yeah.net+86 18610265968

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026