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Application of continuous infusion of rocuronium in open hepatectomy

Continuous versus intermittent rocuronium for open hepatectomy: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100047154
Enrollment
Unknown
Registered
2021-06-08
Start date
2016-03-01
Completion date
Unknown
Last updated
2022-01-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatectomy

Interventions

1:intermittent rocuronium infusion
2:continious rocuronium infusion

Sponsors

Zhongshan Hospital, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing elective open partial hepatectomy; 2. Aged 18 to 65 years; 3. BMI(body mass index) between 18 and 30 kg/m2; 4. ASA grade I or II; 5. Class A Child-Pugh classification.

Exclusion criteria

Exclusion criteria: 1. Contraindicated for epidural anesthesia; 2. Preoperative deep vein thrombosis (DVT) of lower extremities; 3. Concurrent neuromuscular diseases; 4. Severe respiratory and cardiovascular diseases, severe hepatic or renal dysfunction; 5. Alcoholism, abuse of any drugs, including narcotics.

Design outcomes

Primary

MeasureTime frame
The degree of satisfaction to muscle relaxation reported by surgeon;—

Secondary

MeasureTime frame
Extubation time;TOF ratio at extubation time;VAS (visual analog scale) reported at PACU, 24h and 48h postoperatively;Postoperative complications including PONV, pruritus, lung infections and effusion in the surgical site;—

Countries

China

Contacts

Public ContactCang Jing

Department of Anesthesiology, Zhongshan Hospital

cang.jing@zs-hospital.sh.cn+86 13916010421

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026