stroke
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with stroke by clinical evaluation and comprehensive imaging examination met the diagnostic criteria established by the National Cerebrovascular Academic Conference in 2014; 2. Fugl-Meyer motor function score was confirmed to be motor dysfunction, and >1 in the joint exercise assessment item; 3. Aged from 18 to 70 years, male or female; 4. No cognitive impairment or communication impairment, simple mental status test (MMSE) more than 27 points; 5. First onset, course of disease 2 days to 6 months.
Exclusion criteria
Exclusion criteria: 1. Patients with heart and lung diseases and other serious systemic diseases who cannot tolerate rehabilitation treatment; 2. Diagnosed with mental illness, major depression (suicidal tendencies) or epilepsy, with a family history of mental illness or epilepsy; 3. Diabetes, uremia and other serious systemic diseases; 4. Severe joint contracture; 5. Suffer from any cause of consciousness disorder; 6. According to the safety guidelines have transcranial direct current/magnetic stimulation (TMS/TDCS) and functional magnetic resonance (fMRI) examination of contraindications such as: there are metal foreign bodies in the body or other implants in the body of electronic devices; 7. Hearing or visual impairment may affect assessment and treatment; 8. The application of drugs to change the excitability of the cerebral cortex (antiepileptic drugs, sedative and hypnotic drugs, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pper limb Fugl-Meyer motor function score and changes; | — |
Secondary
| Measure | Time frame |
|---|---|
| Muscle strength score of affected limb;Modified Barthel Index;Hand function assessment;Electrophysiological examination of affected side nerve;Near-infrared functional imaging; | — |
Countries
China