Effect of low temperature irrigation on the curative effect and prognosis of SMILE operation

Effect of intraoperative low-temperature irrigation on the ultra-early clinical efficacy and prognosis of SMILE surgery

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100047127

Enrollment

Unknown

Registered

2021-06-08

Start date

2021-06-01

Completion date

Unknown

Last updated

2022-01-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

keratorefractive surgery

Interventions

Experimental group:Low temperature irrigation

Experimental group:Room temperature irrigation

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Aged 18 years old, patients has stable myopia and needs to remove glasses; 2.Stop wearing the soft mirror for more than 2 weeks; 3.Stop wearing hard mirror for more than 4 weeks.

Exclusion criteria

Exclusion criteria: 1.Any eye surgery history, anterior segment disease, active lesion and fundus lesion; 2.Suspicious or keratoconus; 3.Severe dry eye; 4.Diabetes mellitus, whole body connective tissue disease or autoimmune dysfunction.

Design outcomes

Primary

Measure	Time frame
Postoperative visual acuity;	—

Secondary

Measure	Time frame
Questionnaire survey of eye irritation symptoms;Opaque bubble layer;Diffuse lamellar keratitis;	—

Countries

China

Contacts

Public ContactLi Weili

Shenzhen Hospital of Southern Medical University

eyelwl@qq.com+86 18575536393

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026