myelosuppression after chemotherapy
Conditions
Interventions
experimental group:umbilical cord blood
Sponsors
Shaanxi People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. AML patients with confirmed diagnosis of bone marrow morphology and immunology; 2. Bone marrow morphology or molecular level excludes APL; 3. Patients with myelosuppression above grade II after chemotherapy; 4. No age and gender limit; 5. Liver and kidney function: blood bilirubin <= 35µmol/L, AST/ALT below 2 times the upper limit of normal, blood muscle liver <= 150µmol/L; 6. Normal heart function; 7. Obtain an informed consent form signed by the patient or family member.
Exclusion criteria
Exclusion criteria: 1. Allergic to any of the drugs involved in the plan; 2. Past intolerance to similar drugs or history of allergies; 3. There are obvious contraindications to chemotherapy drugs; 4. Active tuberculosis patients and HIV-positive patients; 5. Suffer from malignant tumors of other organs at the same time; 6. Suffer from other blood system diseases at the same time; 7. Cannot understand or follow the research plan; 8. The investigator judged that it is not suitable to participate in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| hematological indicators to return to normal levels; | — |
Secondary
| Measure | Time frame |
|---|---|
| changes in the grade of bone marrow suppression;changes in the KPS score;incidence of bleeding;incidence of infection ; | — |
Countries
China
Contacts
Public ContactWang Yi
Shaanxi People's Hospital
Outcome results
None listed