Study on the characteristics and intervention of the first night effect in healthy people

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100047012

Enrollment

Unknown

Registered

2021-06-07

Start date

2021-06-03

Completion date

Unknown

Last updated

2023-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Insomnia

Interventions

Control Group:Blank control

placebo group:placebo

Melatonin group:Melatonin

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Sign the informed consent form; 2. Meet the standards of healthy sleepers reported in the literature; 3. Age 18-65, no gender limit, Han nationality, right-handed; 4. Junior high school and above, MMSE>=24 points; 5. The daily bedtime in the past three months was between 9pm and 1am, and the daily bedtime was >=7 hours every night.

Exclusion criteria

Exclusion criteria: 1. Currently or in the past suffering from mental illnesses and sleep disorders diagnosed by DSM-5; 2. Severe physical illness, night shift in the first 3 months or travelers crossing two time zones; 3. Take drugs that affect sleep at least 2 weeks before participating in the trial; during pregnancy and lactation.

Design outcomes

Primary

Measure	Time frame
Polysomnography;	—

Countries

China

Contacts

Public ContactHu Sifan

Peking University Sixth Hospital/Institute of Mental Health

husifan@bjmu.edu.cn+86 18811501577

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026