Pleth variability index for intraoperative goal-directed fluid therapy in young children undergoing major neurosurgery: a randomized, controlled trial

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100047003

Enrollment

Unknown

Registered

2021-06-06

Start date

2021-10-01

Completion date

Unknown

Last updated

2022-01-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

intraoperative fluid therapy

Interventions

group 1:PVI-guided fluid therapy

group 2:blood pressure-guided fluid therapy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ASA I-II children aged 0-3 years scheduled for elective intracranial epileptic foci excision under general anesthesia.

Exclusion criteria

Exclusion criteria: 1. Operation time <30min; 2. Severe cardiovascular disease; 3. Severe respiratory diseases such as bronchopulmonary dysplasia; 4. Severe intracranial hypertension; 5. The guardian refuses to participate in the trial; 6. Has participated in other clinical studies.

Design outcomes

Primary

Measure	Time frame
fluid volume;blood lactate;	—

Secondary

Measure	Time frame
postoperative major complications;postoperative length of hospital stay;	—

Countries

China

Contacts

Public ContactSong Linlin

Peking University First Hospital

songlinlinlynkia@163.com+86 10 83575138

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026