Aortic stenosis
Conditions
Interventions
The experimental group:Left bundle branch area pacing and Guideline-guided medication
The control group:Guideline-guided medication
Sponsors
Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients after TAVR; 2. New left bundle branch block after surgery, lasting more than 3 months; 3. The absolute value of GLS in heart ultrasound was less than 20% in 3 months after operation; 4. Patients who can understand the purpose of the study, voluntarily participate in and sign an informed consent form, and are willing to accept relevant examinations and clinical follow-ups.
Exclusion criteria
Exclusion criteria: 1. Atrial fibrillation; 2. Past pacemaker implantation; 3. Pacemaker implantation is required due to atrioventricular block after operation; 4. Postoperative patients have been indicated for CRT implantation in accordance with the guidelines for heart failure; 5. Infective endocarditis during the active period or other infections considered by researchers to affect surgery; 6. Participated in other clinical trials in the last 3 months or are participating in other clinical trials; 7. Vulnerable groups, including people with mental illness, cognitive impairment, critically ill patients, minors, and pregnant women; 8. The researcher judges that the compliance is not good; 9. Any other circumstances that the investigator considers inappropriate to participate in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| echocardiography results;N-terminal pro-brain natriuretic peptide;Heart function classification; | — |
Countries
China
Contacts
Public ContactFu Guosheng
Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University
Outcome results
None listed