Acute respiratory distress sydrome Intra-abdominal hypertension
Conditions
Interventions
experimental group :prone ventilation
control group:N/A
Sponsors
Center of Severe Acute Pancreatits, Department of Critical Care Medicine,Jinling Hospital, Nanjing Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Mechanical ventilation of tracheal intubation for treatment of ARDS is less than 48 hours; 2. Moderate to severe acute respiratory distress syndrome (defined as moderate to severe ARDS: Pao2: Fio2=5 cm H2O, Fio2 >= 0.6, there is imaging evidence of bilateral lung infiltration, and you cannot be careful Respiratory failure explained by decay or liquid overload (defined according to the Berlin standard); 3. Abdominal hypertension level 1 and 2 (IAP measurement value is 12-20mmHg); 4. It is expected that the tube will not be extubated offline within 48 hours.
Exclusion criteria
Exclusion criteria: 1. Intracranial pressure> 30 mm Hg or cerebral perfusion pressure <60 mm Hg; 2. Major hemoptysis requires immediate surgical operation or interventional operation; 3. Perform tracheal surgery or sternotomy within the first 15 days; 4. Severe facial trauma or facial surgery in the first 15 days; 5. Treatment of deep vein thrombosis is less than 2 days; 6. Built-in pacemaker in the past 2 days; 7. Fractures of the spine, femur or pelvis; 8. The average arterial pressure is less than 65 mmHg; 9. Pregnant women; 10. Leakage of chest drainage tube.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IAPmean at day3; | — |
Countries
China
Contacts
Public ContactTong Zhihui
Center of Severe Acute Pancreatits, Department of Critical Care Medicine,Jinling Hospital, Nanjing Medical University
Outcome results
None listed