biliary atresia
Conditions
Interventions
Control Group:Conventional therapy
Experimental group:Belimumab
Sponsors
Guangzhou Women and Children Medical Center
Eligibility
Sex/Gender
All
Age
0.1 Years to 0.3 Years
Inclusion criteria
Inclusion criteria: 1. The subjects of this study were recruited from the Hepatobiliary Surgery Department of Guangzhou Women and Children's Medical Center who were diagnosed with highly suspected BA by experienced doctors, and the patients were planned to undergo hepatobiliary surgery; 2. 0-3 months old children with obstructive jaundice; 3. A clear diagnosis of BA by intraoperative cholangiography; 4. Normal hematopoietic function; 5. The guardian's informed consent.
Exclusion criteria
Exclusion criteria: 1. Children with systemic inflammatory response syndrome or multiple system malformations; 2. Children with unclear diagnosis of the primary disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Liver function indexes;Lymphocytes count;Detection of autoantibody;BAFF concentration; | — |
Countries
China
Contacts
Public ContactWen Zhe
Guangzhou Women and Children Medical Center
Outcome results
None listed