knee osteoarthritis
Conditions
Interventions
drug treatment+IPFH intervention subgroup:oral celecoxib + flurbiprofen ester paste+comprehensive and individualized practice plan
drug treatment+control subgroup:oral celecoxib + flurbiprofen ester paste+regular health and disease education
pain points injection treatment+IPFH intervention subgroup:peri-knee pain point injection of lidocaine and dexamethasone palmitate or betamethasone sodium phosphate mixture+comprehensive and individua
pain points injection treatment+control subgroup:peri-knee pain point injection of lidocaine and dexamethasone palmitate or betamethasone sodium phosphate mixture+regular health and disease education
combined treatment +IPFH intervention subgroup:intra-articular injection of chitosan or platelet-rich plasma or sodium hyaluronate + peri-knee pain point injection of lidocaine and dexamethasone palmi
combined treatment +control subgroup:intra-articular injection of chitosan or platelet-rich plasma or sodium hyaluronate + peri-knee pain point injection of lidocaine and dexamethasone palmitate or be
Sponsors
Sanbo Brain Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with joint pain as the chief complaint; 2. Meet the diagnostic criteria of knee osteoarthritis; 3. Feasible clinical standard treatment in pain department; 4. Voluntarily participate in active health management and actively implement active health guidance programs; 5. No disease with impaired consciousness and cognitive decline, able to communicate and interact normally; 6. Have a smart phone and be able to use it normally.
Exclusion criteria
Exclusion criteria: 1. Are participating in other intervention measures; 2. Knee osteoarthritis caused by other systemic diseases; 3. Lack of mobile devices that can complete health management.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC); | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of Life (SF-36);Kellgren and Lawrence grade (KL level);Bone mineral density (BMD);serum inflammatory cytokines (CRP and IL-6);Non-invasive Active Health Index;weekly average pain score(VAS); | — |
Countries
China
Contacts
Public ContactWang Baoguo
Sanbo Brain Hospital, Capital Medical University
Outcome results
None listed