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A randomized controlled clinical study of indobufen combined with clopidogrel and aspirin combined with clopidogrel for antiplatelet therapy after coronary intervention in acute coronary syndrome

A randomized controlled clinical study of indobufen combined with clopidogrel and aspirin combined with clopidogrel for antiplatelet therapy after coronary intervention in acute coronary syndrome

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100046967
Enrollment
Unknown
Registered
2021-06-05
Start date
2021-06-07
Completion date
Unknown
Last updated
2022-01-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute coronary syndrome

Interventions

Group 2:aspirin with clopidogrel
Group 1:indobufen with clopidogrel

Sponsors

Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People’s Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: Patients with acute coronary syndrome.

Exclusion criteria

Exclusion criteria: 1. Severe complications occurred during PCI; 2. Known to be intolerant or allergic to aspirin, clopidogrel and non-steroidal anti-inflammatory drugs; 3. It is expected that the surgical operation that needs to stop the use of antiplatelet drugs will be performed within 1 year; 4. At the same time, oral anticoagulant drugs are required; 5. Past history of cerebral hemorrhage, stroke occurred within six months; 6. Platelets are less than 100 x 10^9/L, and hemoglobin is less than 90g/L; 7. Severe heart, liver and kidney dysfunction, blood system diseases, immunodeficiency diseases, bleeding diseases, malignant tumor diseases, failure of other organs and systems, etc.; 8. Pregnancy or breastfeeding; 9. Inability to understand or obey the research procedures and follow-up.

Design outcomes

Primary

MeasureTime frame
Adverse cardiovascular events;

Countries

China

Contacts

Public ContactTu Xiaoming

Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People’s Hospital

15605706882@163.com+86 15605706882

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026