Refractive Error
Conditions
Interventions
Sponsors
Qingdao Eye Hospital of Shandong First Medical University
Eligibility
Sex/Gender
All
Age
21 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. The spherical power of the patient is -1.00D-- -10.00D, and the power of the cylinder is less than or equal to 5.00D. 2. The patient's refractive power is relatively stable within 2 years. 3. Patients who wear rigid contact lenses need to stop wearing contact lenses for 4 weeks, and soft lenses need to stop wearing them for 2 weeks. 4. For patients who wear contact lenses, the corneal curvature and optometry data on the day of the operation are not much different from the previous examination data (not more than 0.5D). If there is, the operation should be rescheduled after the refractive state is stabilized. 5. The patient's best corrected visual acuity reaches 1.0 or above. 6. The patient's corneal topography is normal. 7. The pupil diameter of the dark room of the patient is between 6-8mm. 8. Aged 21-45 years. 9. Patients need to voluntarily sign an informed consent form. 10. During the study period, patients need to be able to and voluntarily follow up.
Exclusion criteria
Exclusion criteria: 1. The patient has potential, recurring or progressive corneal disease, corneal abnormalities (especially recurrent corneal erosion, severe stromal disease, keratoconus, transparent marginal corneal degeneration) or corneal scars within the scope of surgery. 2. The shape of the cornea of the patient's one or both eyes is irregular. 3. The patient's myopia has progressed. 4. The patient is taking some systemic drugs that may affect wound healing, such as adrenal cortex hormones and antimetabolites. 5. The patient has immune insufficiency or connective tissue disease, dominant genetic disease or diabetes. 6. The patient has a history of eye surgery. 7. Irregular curvature of the patient's central cornea. 8. The patient is allergic to the drugs used in the study. 9. The patient has a history of glaucoma or suspicious glaucoma. 10. The patient participates in other trials during the trial period. 11. The patient has a history of herpetic keratitis. 12. Female patients are pregnant or breastfeeding or planning to become pregnant. 13. The patient may have strabismus after surgery. 14. The patient suffers from systemic diseases, especially vascular diseases, such as rheumatic diseases, systemic lupus erythematosus or sicca. 15. The patient suffers from nystagmus or cannot fix the eyes for a long time during the operation. 16. The thickness of the remaining corneal stroma after the operation is less than 250um.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Corneal epithelial thickness;Corneal topography;Naked eyes and corrected vision;Refractive power;Aberration;Optical area;Corneal curvature;Intraocular pressure;Ablation depth; | — |
Countries
China
Contacts
Public ContactLong Keli
Qingdao Eye Hospital of Shandong First Medical University
Outcome results
None listed