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Effect of corneal epithelial remodeling on clinical outcome after refractive surgery

Effect of corneal epithelial remodeling on clinical outcome after refractive surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100046923
Enrollment
Unknown
Registered
2021-05-31
Start date
2021-06-01
Completion date
Unknown
Last updated
2022-01-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Refractive Error

Interventions

Group 1 :Hormone
Group 2:NSAIDs
Group 3:Anti-glaucoma drugs

Sponsors

Qingdao Eye Hospital of Shandong First Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
21 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. The patient underwent corneal refractive surgery for 6 months or more in Qingdao Eye Hospital. 2. Patients must have had a stable refraction for the last 1 months as documented by previous clinical records. 3. Patients aged 21-45 years. 4. Patients must sign a written Informed Consent form. 5. Patients must be able and willing to return for scheduled follow-up examinations for the duration of the study.

Exclusion criteria

Exclusion criteria: 1. Patients with eye diseases including secondary keratoconus, dry eye, visual fatigue cause pseudomyopia, glaucoma, cataract, corneal clouding, and retinal disease and systemic diseases. 2. Patients missed any follow-up visits within the first three months after surgery. 3. Patients experienced uncontrolled steroid-induced ocular hypertension occurred during postoperative topical corticosteroid administration. 4. Patients who have a known sensitivity to study medication. 5. Women who are pregnant, lactating, or planning to become pregnant over the course of this clinical investigation.

Design outcomes

Primary

MeasureTime frame
Corneal epithelial thickness;Corneal topography;Naked eyes and corrected vision;Refractive power;Optical area;Corneal curvature;Intraocular pressure;Biomechanical parameters;Posterior corneal elevation;Ablation depth;

Countries

China

Contacts

Public ContactLong Keli

Qingdao Eye Hospital of Shandong First Medical University

longkeli2002@aliyun.com+86 18363923979

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026