Mild gastointetinal discomforts
Conditions
Interventions
Experimental group:feeding PHP formula supplement with symbotic
Control group:feeding ordinary formula
Sponsors
The Affiliated Hospital of Qingdao University
Eligibility
Sex/Gender
All
Age
1 Years to 2 Years
Inclusion criteria
Inclusion criteria: 1. Aged 1-2 years; 2. Who has a history of mild milk protein allergy diagnosed by doctors and has recovered; 3. Accompanied by mild diarrhea, constipation, abdominal distension and / or sleep disorders; 4. The patient's Guardian sign the informed consent form to allow the researcher to cooperate with the whole process of clinical trial and collect clinical data and stool samples; 5. Children with normal growth and development agree to maintain the existing intervention program for the next three months.
Exclusion criteria
Exclusion criteria: 1. Children with severe multiple food allergy or intolerance; children with lactose intolerance; 2. There was a clear history of brain injury, cerebral palsy, encephalitis and other organic diseases; 3. The patients with other diseases were definitely diagnosed; 4. There are intestinal organic diseases, such as Hirschsprung's disease, intestinal obstruction, intussusception, etc; 5. Using antiallergic drugs and psychotropic drugs; 6. Probiotics, antibiotics, acid inhibitors and other drugs that affect the intestinal flora were used in the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Questionnaires; | — |
Countries
China
Contacts
Public ContactWang Yanxia
The Affiliated Hospital of Qingdao University
Outcome results
None listed