Spontaneous cerebral hemorrhage, traumatic brain injury
Conditions
Interventions
experimental group:For patients with systolic blood pressure 150-220 mmHg, lower the blood pressure to 130-140 mmHg
for patients with systolic blood pressure >220 mmHg, the target systolic blood pressure is 160 mmHg and computed tomography is performed within 6 hours.
control group:For patients with systolic blood pressure 150-220 mmHg, lower the blood pressure to 160 mmHg
for patients with systolic blood pressure >220 mmHg, the target systolic blood pressure is 180 mmHg, and computed tomography is performed 6 hours after the operation.
Sponsors
Yibin Second People's Hospital
Eligibility
Sex/Gender
All
Age
16 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged > 16 years and = 150 mmHg): (1) Craniotomy and hematoma removal is required for craniocerebral trauma; (2) Hemorrhage in the basal ganglia and thalamus: 1) The volume of basal ganglia hematoma exceeds 30ml, and the volume of temporal lobe hematoma exceeds 20ml; 2) Uncooked temporal lobe hernia; 3) There are obvious manifestations of intracranial hypertension in imaging (the midline structure shifts more than 5 mm; the ipsilateral ventricle is compressed and occluded more than 1/2; the ipsilateral cistern and sulci are blurred or disappeared). 3. No other serious diseases, which seriously affect the prognosis of patients (except hypertension). 4. Craniotomy was performed for the first time in this case, and there was no history of operation on the approach site of this operation.
Exclusion criteria
Exclusion criteria: 1. Preoperative dilated pupils on both sides and unstable vital signs; 2. Have blood system diseases and long-term oral anticoagulant coagulation dysfunction; 3. The condition continued to deteriorate after the operation, the vital signs were unstable, and the brain CT examination could not be performed; 4. Postoperatively diagnosed as a patient with secondary malignant hypertension; 5. Preoperatively confirmed as tumor stroke, cerebral aneurysm rupture, cerebral vascular malformation hemorrhage; 6. Simple traumatic epidural hematoma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rebleeding rate of surgical wound; | — |
Secondary
| Measure | Time frame |
|---|---|
| Does the amount of bleeding require reoperation (evacuation of hematoma by craniotomy or decompressive craniectomy);Fatality rate;Neurological dysfunction rate (including hemiplegia, aphasia, etc.); | — |
Countries
China
Contacts
Public ContactJiang Jingcheng
Yibin Second People's Hospital
Outcome results
None listed