Comparison of retrograde and spot botulinium toxin injection in the treatment of forehead, glabellar, and periorbital wrinkles: a prospective, single-blind, randomized clinical trial

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100046880

Enrollment

Unknown

Registered

2021-05-29

Start date

2021-06-01

Completion date

Unknown

Last updated

2022-01-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Group 1:Linear injection on one side

Group 2:One side spot injection

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients aged > 18 years, meet the criteria of minimally invasive surgery, and have dynamic wrinkles on the upper face; 2. All patients have informed consent and voluntarily receive minimally invasive injection treatment.

Exclusion criteria

Exclusion criteria: 1. Diseases of the blood system, nervous system and immune system; 2. Blood coagulation dysfunction; 3. History of mental illness; 4. Pregnant and lactating women; 5. Communication barriers; 6. Poor cooperation and the corresponding contraindications for surgery.

Design outcomes

Primary

Measure	Time frame
Wrinkle scale;Muscle movement;	—

Countries

China

Contacts

Public ContactLong Xiao

Peking Union Medical College Hospital

pumclongxiao@126.com+86 13810193175

Outcome results