Perioperative Neurocognitive Disorders
Conditions
Interventions
experimental group:0.5% ropivacaine + 1µg/kg dexmedetomidine, 20ml
Sponsors
Yibin Second People's Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. All participants have signed an informed consent form; 2. Aged >= 60 years; 3. American society of anesthesiologists (American society of anesthesiologists, ASA) classification I-III; 4. Operation time >= 120min; 5. The preoperative activities of daily living (ADLs) score >= 95 points.
Exclusion criteria
Exclusion criteria: 1. Patients with mental and psychological disorders; 2. Long-term history of alcohol and drug abuse, long-term use of Valium or opioids; 3. Preoperative mini-mental state examination (MMSE) scores to determine patients with postoperative cognitive dysfunction (such as patients with Alzheimer's disease); 4. Those who have adverse reactions to the anesthetics used; 5. Patients with infection and abnormal blood coagulation at the puncture site; 6. Patients with diabetes and severe organ dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Perioperative incidence of neurocognitive impairment; | — |
Countries
China
Contacts
Public ContactYu Deshui
Yibin Second People's Hospital
Outcome results
None listed