Localized scleroderma
Conditions
Interventions
Intervention group:Topical benvimod drugs
Sponsors
The Second Xiangya Hospital of Central South University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. No gender limit, aged 18-65 years; 2. Two dermatologists at the level of attending and above were jointly diagnosed as active localized scleroderma within 2 weeks before participating in the study; 3. Before participating in the research, do not use any topical medications or systemic medications.
Exclusion criteria
Exclusion criteria: 1. Disagree to participate in research during the informed consent process; 2. Patients with localized scleroderma who only have skin lesions on the head and face; 3. There are other serious basic diseases (such as coronary heart disease, pulmonary embolism, cerebrovascular accident, etc.); 4. Patients who are pregnant, planning to become pregnant or breastfeeding; 5. Patients with neurological or psychiatric diseases or potentially poor compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified localized scleroderma skin severity index;Cutaneous induration; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual analogue scale;Ultrasonophy;Skin biopsy; | — |
Countries
China
Contacts
Public ContactXiao Rong
The Second Xiangya Hospital of Central South University
Outcome results
None listed