Precancerous lesions of the lower reproductive tract
Conditions
Interventions
Group Two:Photodynamics Therapy
Group One:Undergoing Leep operation
Group Three:Undergoing surgery
Group Four:Undergoing electric burning
Group Five:With drug treatment, 5-FU, VP-16, etc.
Sponsors
Peking University Shenzhen Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: The patients were 20-65 years old and had a history of sexual life. 1. Vulvar intraepithelial lesions :VIN II, VIN III; 2. Patients with vaginal intraepithelial lesions: VaIN II, VaIN III; 3. Patients with cervical intraepithelial diseases: CIN II, CIN III; 4. The combination of 2-3 parts mentioned above.
Exclusion criteria
Exclusion criteria: 1. Patients with hemoporphyria; 2. Patients with confirmed malignant tumors of the lower reproductive tract; 3. The treatment area had received other treatment methods: cervical lesions had received cervical drugs (e.g., 5-FU, VP-16), physical, conical or total hysterectomy; vulva and vaginal lesions had received drug (e.g., 5-FU, VP-16), physical or surgical treatment 4. Pregnancy or lactation; 5. Active period of general infectious diseases; 6. Patients with hepatic failure; 7. Patients with severe mental disorder.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cure rate;Response rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| HPV eradication rate; | — |
Countries
China
Contacts
Public ContactLi Ruizhen
Peking University Shenzhen Hospital
Outcome results
None listed