Function of MiR-132 in Perioperative Neurocognitive Dysfunctions in Elderly Patients: protocol for a prospective cohort study

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100046844

Enrollment

Unknown

Registered

2021-05-29

Start date

2021-05-31

Completion date

Unknown

Last updated

2022-01-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative neurocognitive dysfunctions

Interventions

cognitive dysfunction group vs. non cognitive dysfunction grouop:Nil

Eligibility

Sex/Gender

All

Age

60 Years to 120 Years

Inclusion criteria

Inclusion criteria: Patients over 60 years old scheduled to undergo elective non-cardiac, non-neurological surgery under general anaesthesia from 2021 to 2023 will be recruited consecutively for eligibility screening.

Exclusion criteria

Exclusion criteria: 1. Previous diagnosis of diseases related to neurocognitive dysfunction; 2. Prior neurosurgery; 3. Previous heart surgery; 4. Previous traumatic brain injury; 5. History of depression; History of epilepsy; 6. Short operation (anesthesia duration less than 1 hour); 7. Unable to complete the cognitive function assessment in the study; 8. Refusal to sign informed consent; 10. Incomplete clinical data.

Design outcomes

Primary

Measure	Time frame
Cumulative incidence of perioperative neurocognitive dysfunctions;	—

Secondary

Measure	Time frame
Postoperative delirium;Recovery quality;Quality of life;Depression state;Biomarkers;Clinical outcomes;	—

Countries

China

Contacts

Public ContactWu Bei

Beijing Tian Tan Hospital, Capital Medical University

luckybei0705@163.com+86 15001254592

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026