The research on iodine requirement in Chinese young adults
Conditions
Interventions
1:Normal dietaty iodine intake
2:one-time 60 g kelp intake or 600 µg iodine-containing potassium iodide
3:one-time 60 g kelp intake or 600 µg iodine-containing potassium iodide
Sponsors
National Institute of Nutrition and Health, Chinese Center for Disease Control and Prevention
Eligibility
Sex/Gender
All
Age
18 Years to 25 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-25 years; 2. BMI of 19-25 kg/m2; 3. Adequate iodine status (defined as urinary iodine concentration > 100 µg/L assessed during screening from random urine samples); 4. Daily defecation regularity, and comply the rules of study during the 20 days; 5. Accomplish the collection of biosamples according to the regular requirement.
Exclusion criteria
Exclusion criteria: 1. Abnormal routine blood and urine tests, thyroid dysfunction, metabolic disorders, gastrointestinal diseases, and other chronic diseases or long-term substance abuser. Irregular defecation or over 3-days interval or constipation personnel; 2. Abnormal iodine status or exposure to iodine-containing contrast agents within the last 6 month or use of iodine-containing skin disinfectants and supplements within 1 month or other diseases affecting absorption and metabolism of iodine.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dietary iodine intake;Urinary iodine concentration;24-hour urinary iodine excretion;fecal iodine excretion;Iodine speciation; | — |
Countries
China
Contacts
Public ContactYang Xiaoguang
National Institute of Nutrition and Health, China CDC
Outcome results
None listed