essential hypertension
Conditions
Interventions
Sponsors
Institute of Basic Theory of Chinese Medicine, China Academy of Chinese Medicine Science
Eligibility
Sex/Gender
All
Age
45 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 40-75 years, male or female; 2. Meet the diagnostic criteria of essential hypertension; 3. 24-hour blood pressure rhythm is non-spoon type; 4. The regimen of western medicine for hypertension is stable (more than 3 months); 5. Voluntarily participate in the trial and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. People who are known or suspected to be allergic to experimental drugs and their components; 2. Patients with familial hypertension, malignant hypertension, hypertensive emergency, hypertensive crisis and hypertensive encephalopathy; 3. There is evidence of secondary hypertension, including but not limited to the following diseases: unilateral or bilateral renal artery stenosis, polycystic kidney disease, aldosteronism, coarctation of the aorta, Cushing syndrome, pheochromocytoma. 4. Gastrointestinal lesions or gastrointestinal surgery may affect drug absorption or excretion, such as gastroenterectomy, active gastrointestinal inflammation within nearly 3 months, ulcers or gastrointestinal bleeding; 5. Lifestyle with day and night reversal, or irregular sleep patterns; 6. People with a history of alcohol or drug abuse; 7. Inability to cooperate because of neurological or mental disorders; 8. Pregnant, lactating women or people with recent fertility plans; 9. The researchers do not think it is appropriate to participate in this clinical trial; 10. They have participated in other clinical trials within 3 months before the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Spoon blood pressure recovery rate;Blood pressure variability index;Effective rate of blood pressure reduction(clinic blood pressure); | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes of home blood pressure monitoring compared with baseline ;Changes of clinic blood pressure relative to baseline;The rate of reaching the standard rate of blood pressure in the clinic; | — |
Countries
China
Contacts
Public ContactHu Jingqing
Institute of Basic Theory of Chinese Medicine, China Academy of Chinese Medicine Science
Outcome results
None listed