postoperative cognitive dysfunction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Informed consent; 2. Aged from 40 to 80 years; 3. ASA grade I-III; 4. The preoperative examination was improved to meet the indications of elective abdominal surgery.
Exclusion criteria
Exclusion criteria: 1. MMSE score < 24; 2. CT examination ruled out organic brain injury; 3. Have epilepsy, anxiety and depression and other nervous, psychological system diseases or serious physical diseases; 4. Patients with a previous brain disease; 5. Drug dependence, substance abuse or use of anticonvulsants, sedatives, or depressants in the past three months; 6. Audio-visual impairment, chronic insomnia; 7. Patients unable to visit and communicate due to other reasons; 8. Patients may have or have had a difficult airway.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Susceptibility gene;Mini-Mental State Examination;Digit span test;Stroop test;Trail Making Test A and B;Verbal Fluency test; | — |
Countries
China
Contacts
Department of Anesthesiology, the First Affiliated Hospital, Anhui Medical university