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The study of identification susceptibility genes and its risks of postoperative cognitive dysfunction

The study of identification susceptibility genes and its risks of postoperative cognitive dysfunction

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100046822
Enrollment
Unknown
Registered
2021-05-28
Start date
2021-05-27
Completion date
Unknown
Last updated
2022-01-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative cognitive dysfunction

Interventions

postoperative cognitive dysfunction (POCD) group:Nil
non POCD group:Nil

Sponsors

Department of Anesthesiology, the First Affiliated Hospital, Anhui Medical university
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1. Informed consent; 2. Aged from 40 to 80 years; 3. ASA grade I-III; 4. The preoperative examination was improved to meet the indications of elective abdominal surgery.

Exclusion criteria

Exclusion criteria: 1. MMSE score < 24; 2. CT examination ruled out organic brain injury; 3. Have epilepsy, anxiety and depression and other nervous, psychological system diseases or serious physical diseases; 4. Patients with a previous brain disease; 5. Drug dependence, substance abuse or use of anticonvulsants, sedatives, or depressants in the past three months; 6. Audio-visual impairment, chronic insomnia; 7. Patients unable to visit and communicate due to other reasons; 8. Patients may have or have had a difficult airway.

Design outcomes

Primary

MeasureTime frame
Susceptibility gene;Mini-Mental State Examination;Digit span test;Stroop test;Trail Making Test A and B;Verbal Fluency test;

Countries

China

Contacts

Public ContactXu Guanghong

Department of Anesthesiology, the First Affiliated Hospital, Anhui Medical university

xuguanghong2004@163.com+86 13856949535

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026