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Effect of PI3K/AKT signaling pathway on GABA A receptor expression, regulation and prognosis in small for gestational age infants with brain injury

Effect of PI3K/AKT signaling pathway on GABA A receptor expression, regulation and prognosis in small for gestational age infants with brain injury using MRI

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100046816
Enrollment
Unknown
Registered
2021-05-28
Start date
2022-01-01
Completion date
Unknown
Last updated
2022-01-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

neonatal brain injury

Interventions

Gold Standard:Clinical data, laboratory examination and MRI results.
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blood.

Sponsors

Qi Ying
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 2 Years

Inclusion criteria

Inclusion criteria: 1. Neonates from Shengjing Hospital of China Medical University; 2. Healthy and SGA newborns 1-2 days after birth (SGA newborns are defined as newborn birth weight is less than two standard deviations of the mean birth weight for the same gestational age and sex.); 3. Obtain informed consent from the guardian and consent from the Ethics Committee.

Exclusion criteria

Exclusion criteria: 1. Intracranial infection, hereditary metabolic encephalopathy and congenital malformation.

Design outcomes

Secondary

MeasureTime frame
birth weight;—

Countries

China

Contacts

Public ContactQi Ying

Shengjing Hospital of China Medical University

womanman1982@163.com+86 18940258254

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026