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The Impact of Circadian Rhythm on the Immune Reaction to Vaccine against SARS-CoV-2

The Impact of Circadian Rhythm on the Immune Reaction to Vaccine against SARS-CoV-2

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100046815
Enrollment
Unknown
Registered
2021-05-28
Start date
2021-05-31
Completion date
Unknown
Last updated
2022-01-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Novel Coronavirus Pneumonia (COVID-19)

Interventions

Morning vaccination group:Vaccination between 8 am-12 pm
Afternoon vaccination group :Vaccination between 4 pm-6 pm

Sponsors

The First Affiliated Hospital of Guangzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Adults who are vaccinated against SARS-CoV-2 for the first time.

Exclusion criteria

Exclusion criteria: 1. A history of COVID-19 infection; 2. Have been vaccinated against SARS-CoV-2 in the past or have received any vaccine 3 months before enrollment; 3. Patients with immunodeficiency, cancer, diabetes, and chronic inflammatory diseases; 4. Those who are using systemic drugs: such as intravenous hormones, opioids; 5. Patients with contraindications to vaccine against SARS-CoV-2; 6. People who are using immunosuppressive agents; 7. Patients with mental disorders; 8. Patients with obstructive sleep apnea and insomnia who have been treated.

Design outcomes

Primary

MeasureTime frame
SARS - Cov2 specificity antibody;neutralizing antibody;specific T cells;memorable B cells;—

Countries

China

Contacts

Public ContactZhang Nuofu

The First Affiliated Hospital of Guangzhou Medical University

nfzhanggird@163.com+86 13600460056

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026