Acute decompensated heart failure
Conditions
Interventions
ADHF group:Drug therapy
Control group:None
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18 to 85 years; 2.Cardiac function grade III-IV (NYHA); 3.Symptoms and signs typical of chronic heart failure such as decreased exercise tolerance and fluid The 4.The diagnostic cut-off value of amino terminal B-type natriuretic peptide precursor (NT-probNP) was: =450ng/L; Patients aged 50-75 years >=900ng/L; >75 years old patients >=1800 ng/L; 5.Systolic or diastolic dysfunction was suggested by echocardiography.
Exclusion criteria
Exclusion criteria: 1.Severe arrhythmias affect hemodynamics; 2.Recent history of trauma and surgery; 3.Patients with autoimmune disease, malignant tumor or severe hepatorenal insufficiency; 4.Patients with pulmonary embolism, chronic obstructive pulmonary disease, cerebrovascular accident and thyroid dysfunction; 5.Restricted cardiomyopathy, hypertrophic obstructive cardiomyopathy and constrictive pericarditis; 6.Patients with incomplete clinical data; 7.Life expectancy of other serious diseases is not more than one year; 8.Unwilling to sign an informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rehospitalized for heart failure;Cardiac death; | — |
Secondary
| Measure | Time frame |
|---|---|
| All-cause mortality;Cardiocerebral events; | — |
Countries
China
Contacts
Public ContactMeng Xin
Shanghai Sixth People's Hospital
Outcome results
None listed