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Effects of spousal seminal plasma injection before freeze-thaw embryo transfer on clinical pregnancy rates in a population with repeated transplantation failure: a randomized controlled clinical study

Effects of spousal seminal plasma injection before freeze-thaw embryo transfer on clinical pregnancy rates in a population with repeated transplantation failure: a randomized controlled clinical study

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100046803
Enrollment
Unknown
Registered
2021-05-28
Start date
2021-05-28
Completion date
Unknown
Last updated
2022-01-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Reproductive health and Infertility

Interventions

treatment group:intrauterine seminal plasma injection before transplantation
control group:none

Sponsors

Chengdu Women's and Children's Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 39 Years

Inclusion criteria

Inclusion criteria: 1.Patients with frozen and thawed embryo transplantation in Chengdu Women's and Children's Central Hospital; 2.Repeated transplant failure (RIF) population; 3.Male and female are aged 20 to 39 years; 4.Transplantable embryos of good quality; 5.Both male and female are negative for infectious diseases; 6.The man can discharge semen by himself; 7.Agree to participate in the study and sign informed consent.

Exclusion criteria

Exclusion criteria: 1.Patients with acute genital tract infection; 2.Patients with serious heart, brain and lung diseases and serious liver and kidney dysfunction; 3.Persons with severe mental illness, including dementia and mental disorders; 4.Patients with highly allergic constitution; 5.Patients diagnosed of endometritis without treatment.

Design outcomes

Primary

MeasureTime frame
clinical pregnancy rate;

Countries

China

Contacts

Public ContactCui Ling

Chengdu Women's and Children's Central Hospital

306127582@qq.com+86 18181422637

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026