Study on the correlation between intracortical inhibition or facilitation and motor cortex plasticity

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100046794

Enrollment

Unknown

Registered

2021-05-28

Start date

2021-05-28

Completion date

Unknown

Last updated

2022-01-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy young subjects

Interventions

Healthy young subjects group 1:None

Healthy young subjects group 2:Non

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1.Male or female; 2.Agree to accept the intervention of iTBS and cTBS; 3.Agree with and have the ability to learn the procedure, including an adequate level of cognitive understanding; 4.Aged 18 to 50 years; 5.Junior high school or above culture level.

Exclusion criteria

Exclusion criteria: 1.Childhood traumatic experiences (physical, psychological, sexual abuse); 2.Meet the current criteria for major depression, bipolar disorder, schizophrenia, any mental illness (including drug-induced mental illness) and current drug-induced mood disorders; 3.Delusion, dementia, amnesia, obsessive-compulsive disorder, post-traumatic stress disorder, anxiety disorder, any personality disorder, and cognitive or dissociative disorder; 4.Have a history of serious physical disease, heart disease, cardiac pacemaker or implanted drug pump, etc.; 5.Serious negative ideas and behaviors; 6.Pregnant women and lactating women; 7.Intracranial metal implants, cochlear implants, increased intracranial pressure, brain trauma, skull insufficiency, encephalitis, brain tumor; 8.Any neurological diseases, such as epilepsy, Parkinson's disease, stroke, etc., family history of epilepsy, and use of anticonvulsants; 9.Suffer from hypertension and other cardiovascular and cerebrovascular diseases; 10.Cerebral calcification and microhemorrhage were present. 11.Obesity, body mass index(BMI) >35; 12.Sleep deprivation; 13.Patients experience difficulties.

Design outcomes

Primary

Measure	Time frame
Evaluation of plasticity of motor cortex;Double pulse transcranial magnetic evaluation of motor cortex ;Stop signal paradigm ;	—

Countries

China

Contacts

Public ContactHe Chuan

The Affiliated Jiangsu Shengze Hospital of Nanjing Medical University

he-chuan@outlook.com+86 13962106994

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026