Urothelial carcinoma
Conditions
Interventions
Gold Standard:Cystoscopy.
Index test:HK2 abscission cells with abnormal metabolism were sequenced.
Sponsors
The First Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1.Male or female, aged 18 to 90 years; 2.Patients with primary urothelial carcinoma confirmed by pathology and healthy persons without history of malignant tumor; 3.Patients must have normal organ and bone marrow function within 28 days before the study; 4.Subjects voluntarily join the study, sign an informed consent form, have good compliance, and cooperate with follow-up.
Exclusion criteria
Exclusion criteria: 1.Pregnant or lactating women; 2.Participated in another clinical study involving experimental drugs during the most recent treatmen course; 3.Severe and uncontrollable accompanying diseases that may affect protocol compliance or interfere with the interpretation of results; 4.Other malignant tumors in the past 5 years; 5.Have previously received allogeneic hematopoietic stem cell transplantation or solid organ transplantation; 6.HIV positive; Patients who are known to have active hepatitis (ie, hepatitis B or C) are at risk of transmitting the disease through blood or other body fluids; 7.Any other severe, acute or chronic medical or mental illnesses or laboratory abnormalities that may increase the risks, or may interfere with the interpretation of the research results.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Single cell sequencing of HK2 metabolic abnormalities;Urine shedding cells detection;Bladder lens;Pathological examination;B-ultrasonogram;Computed tomography, CT;Urography;SEN, SPE, ACC, AUC of ROC; | — |
Secondary
| Measure | Time frame |
|---|---|
| Age;Gende; | — |
Countries
China
Contacts
Public ContactCheng Jiwen
Urology Department, the First Affiliated Hospital of Guangxi Medical University
Outcome results
None listed