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A randomized controlled clinical study of transscleral cyclophotocoagulation on refractory acute primary angle closure eyes

A randomized controlled clinical study of transscleral cyclophotocoagulation on refractory acute primary angle closure eyes

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100046790
Enrollment
Unknown
Registered
2021-05-28
Start date
2021-06-01
Completion date
Unknown
Last updated
2022-01-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma

Interventions

Control group:Paracentesis of anterior chamber

Sponsors

Tianjin Medical University Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.At least two of the following symptoms: headache, eye pain, nausea, vomiting, intermittent vision loss and rainbow vision; 2.At least three of the following physical signs: conjunctival hyperemia, corneal epithelial edema, moderately dilated and fixed pupils, shallow anterior chamber, angle closure, and lens glaucoma spots; 3.Acute intraocular pressure rise, intraocular pressure (IOP) that cannot be controlled by drugs (a variety of local intraocular pressure lowering drugs are difficult to control intraocular pressure in the normal range within 24-48h); 4.The contralateral eye of patients with monocular disease also has the ocular anatomical features of shallow anterior chamber and narrow angle.

Exclusion criteria

Exclusion criteria: 1.Combined with other retinal and optic nerve diseases, obvious systemic and intracranial diseases; 2.Secondary glaucoma; 3.History of previous eye surgery.

Design outcomes

Primary

MeasureTime frame
Intraocular pressure;

Secondary

MeasureTime frame
Visual acuity;Anterior chamber depth;Angle examination;Examination of retinal nerve fiber layer thickness;Degree of corneal edema;Eye pain degree;Complications;Types of drugs used to lower intraocular pressure after surgery;Ocular ultrasound microscopy;Routine eye examination;

Countries

China

Contacts

Public ContactLiu Wei

Tianjin Medical University Eye Hospital

remmusliu@gmail.com+86 22 86428705

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026