Patients undergoing elective cardiac surgery
Conditions
Interventions
Control group 1:Myofascial plane block, 0.9% sodium chloride, total volume 30ml
MFPB group 1:Myofascia plane block, 0.375% ropivacaine, 30ml
Control group 2:Myofascial plane block with 0.9% sodium chloride, 30ml. Regional block catheter was placed and pulse analgesic pump (0.9% sodium chloride, 8ml/h) was connected
MFPB goup 2:Myofascial plane block, 0.375% ropivacaine, 30ml.Regional block catheter was placed and pulse analgesic pump (0.2% ropivacaine, 8ml/h) was connected
Sponsors
Zhongshan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.No gender limitation, aged 18 to 80 years; 2.ASA classification I-III; 3.Body mass index (BMI) 18-31; 4.NYHA classification I-III; 5.Elective heart surgery; 6.Voluntary participation and signing of informed consent.
Exclusion criteria
Exclusion criteria: 1.Participating in other clinical trials; 2.Surgery with deep hypothermia circulatory arrest surgery, re-surgery or emergency surgery; 3.Patients with preoperative liver or kidney dysfunction (ALT, AST, SCR or BUN increased to more than 1.5 times the normal value); 4.Patients with coronary heart disease, asthma, severe COPD, active infective endocarditis or pulmonary hypertension; 5.Preoperative chronic pain or long-term use of analgesics; 6.Known abuse of alcohol, drugs or narcotics; 7.People who are known to be allergic to research drugs; 8.Dementia or preoperative mental disorders, unable to do not cooperate or communicate; 9.Expected survival time less than 24 hours; 10.Women in pregnancy or lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QoR-15 score; | — |
Secondary
| Measure | Time frame |
|---|---|
| QoR-15 score;Visual analogue scale;The first time patients controlled analgesia demand time;The number of compressions and invalid times for patients with intravenous analgesia;Total amount of sufentanil;Remedial analgesia rate;Exhaust time;Oxygenation index;Mechanical ventilation duration;Duration of intensive care unit stay;Time of thoracic canal removal;The hospitalization time;The comfort score was followed up to assess the occurrence of chronic pain;Routine blood;Blood glucose; | — |
Countries
China
Contacts
Public ContactGuo Kefang
Zhongshan Hospital, Fudan University
Outcome results
None listed