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Influence of driving pressure-guided individualized ventilation strategy on pulmonary complications after laparoscopic surgery in children

Influence of driving pressure-guided individualized ventilation strategy on pulmonary complications after laparoscopic surgery in children

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100046784
Enrollment
Unknown
Registered
2021-05-28
Start date
2021-06-01
Completion date
Unknown
Last updated
2022-01-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric laparoscopic surgery

Interventions

Conventional mechanical ventilation group:10ml/kg tidal volume+ZEEP
Lung protective ventilation strategy group:6ml/kg tidal volume + PEEP + lung recruitment
Drive pressure oriented ventilation strategy group:Adjust PEEP and select the lowest drive pressure

Sponsors

Lanzhou University Second Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 12 Years

Inclusion criteria

Inclusion criteria: 1.Select 60 children who underwent laparoscopic surgery in our hospital from June 2021 to September 2021; 2.American Association of Anesthesiologists (ASA) grading standards I~III; 3.The age of the patient is 6-12 years; 4.Preoperative chest X-rays were normal.

Exclusion criteria

Exclusion criteria: 1.History of congenital heart disease, pneumonia, bronchial asthma, severe heart, brain, and neuromuscular diseases; 2.Patient and family members refused, history of lung surgery; 3.Serious abnormalities in general laboratory examinations before surgery (such as severe anemia, coagulation dysfunction, severe hypoproteinemia, etc.); 4.Transfer patients to laparotomy; 5.Preoperative X-ray shows abnormality or LUS score is greater than 0.

Design outcomes

Primary

MeasureTime frame
Postoperative pulmonary complications;

Secondary

MeasureTime frame
Pulmonary ultrasound index;

Countries

China

Contacts

Public ContactWang YingBin

Lanzhou University Second Hospital

wangyingbin6@163.com+86 13893133264

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026