Effect of trigeminal nerve stimulation with different frequencies on activation of cerebral blood oxygen of frontotemporal lobe in healthy adults

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100046782

Enrollment

Unknown

Registered

2021-05-28

Start date

2021-05-26

Completion date

Unknown

Last updated

2022-01-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

40 Hz group:40 Hz Trigeminal nerve stimulation

80 Hz group:80 Hz Trigeminal nerve stimulation

120 Hz group:120 Hz Trigeminal nerve stimulation

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Aged >=18 years; 2.Right-handed measured by the Edinburgh Handedness Inventory; 3.The subject or his/her family members signed the informed consent voluntarily.

Exclusion criteria

Exclusion criteria: 1.History of neuro-cerebrovascular disease; 2.History of mental illness; 3.Short and long term history of taking cardiovascular drugs; 4.Drug abuse and alcohol dependence; 5.Trauma brain injury or cerebral surgery; 6.Skin defect, infection or large scar of head and face; 7.Pregnancy.

Design outcomes

Primary

Measure	Time frame
Oxygen hemoglobin concentration;	—

Secondary

Measure	Time frame
Functional connectivity strength;ß value;	—

Countries

China

Contacts

Public ContactMa Chao

Department of Rehabilitation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University

ma_chao99@126.com+86 18127880016

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026