Effect of operation timepoint on the incidence of sleep disturbulence and melatonin level in surgical patients

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100046773

Enrollment

Unknown

Registered

2021-05-28

Start date

2021-05-24

Completion date

Unknown

Last updated

2022-05-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

surgery

Interventions

Group M:Surgery in the morning

Group A:Surgery in the afternoon

Eligibility

Sex/Gender

All

Age

65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. The subjects who signed the informed consent; 2. Subjects older than 65 years old; 3. Subjects of ASA grade II-III; 4. Patients scheduled for surgery.

Exclusion criteria

Exclusion criteria: 1. Subjects with contraindications to regional block technique (local anesthetic allergy, infection around puncture site and coagulation disorder); 2. Subjects with a history of dependence on analgesics; 3. Patients with dementia or cognitive impairment (positive in cam and less than 24 in MMSE); 4. Patients with any cerebrovascular accident within 3 months, such as stroke, transient ischemic attack (TIA), etc. 5. Any patient with communication difficulties.

Design outcomes

Primary

Measure	Time frame
Incidence of sleep disturbulence in the two groups;	—

Secondary

Measure	Time frame
Incidence of delirium on the first day after surgery;Melatonin levels in the two groups;The amount of anesthetics, vasoactive drugs and fluids used during the operation;Vasoactive intestinal peptide levels in the two groups;	—

Countries

China

Contacts

Public ContactBin Mei

mb85doc@yeah.net+86 551 62922344

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026