ARDS
Conditions
Interventions
Test group:Sivelestat sodium
Control group:Normal saline
Sponsors
He'nan Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.There is no restriction on gender, over 18 years old; 2.Patients diagnosed with ARDS according to the Berlin ARDS diagnostic guidelines (oxygenation index PaO2/FiO2 <300 mmHg, appendix 1); 3.Patients who can be administered within 72 hours of the onset of ARDS; 4.The doctor performs routine treatment according to the patient's condition; 5.Able to understand and abide by the requirements of the agreement, voluntarily participate in this research and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Patients participating in other clinical studies; 2.Patients with serious lack of diagnosis and treatment data; 3.Women during pregnancy, lactation or women who may be pregnant; 4.According to the judgement of the investigator, patients who are deemed unsuitable for this study group (such as patients with mental illness, patients who may die in a short time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxygenation index;Mechanical ventilation time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammation indicators;Lung imaging indicators;Lung function index;Acute Respiratory Distress Syndrome (ARDS) overall outcome; | — |
Countries
China
Contacts
Public ContactQin Bingyu
He'nan Provincial People's Hospital
Outcome results
None listed