None listed
Conditions
Interventions
group A:Alfentanil 7µg/kg intravenously, followed by a slow injection of propofol 1.5mg/kg
group B:Alfentanil 7µg/kg was injected intravenously during the induction period, followed by intravenous injection of remimazolam 0.1 mg/kg
group C :Alfentanil 7µg/kg was injected intravenously during the induction period, followed by intravenous injection of remimazolam 0.2 mg/kg
group D :Alfentanil 7µg/kg was injected intravenously during the induction period, followed by intravenous injection of remimazolam 0.3 mg/kg
Sponsors
The Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients who intend to undergo gastroscopy, colonoscopy or gastrointestinal endoscopy; 2. Aged 18-65 years, there is no restriction on gender; 3. ASA I-II grade; 4. BMI 18-30kg/m^2; 5. Informed consent, voluntarily participate in the trial, and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Subjects with severe heart, brain, lung, liver, kidney and metabolic diseases; 2. Those who have a history of abnormal surgical anesthesia recovery; 3. ECG prompt: heart rate 180mmHg and (or) diastolic blood pressure >110mmHg, or hypotension patients 40%/150ml wine); 9. Subjects who the researcher thinks are inappropriate to participate in this research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of intraoperative blood pressure reduction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vital signs;Total inspection time;Wake up time;Ramsay sedation score; | — |
Countries
China
Contacts
Public ContactWang Zhiping
The Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed