type 2 diabetes mellitus with coronary artery calcification
Conditions
Interventions
2 diabetes mellitus with coronary artery calcification group vs 2 diabetes mellitus group:Null
Sponsors
The First Affiliated Hospital of University of South China
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years; 2. Definitely diagnose type 2 diabetes in accordance with the WHO diagnostic criteria; 3. Perform a CT scan of the coronary arteries in the serial scan mode during the baseline check; 4. Able to understand the purpose and procedures of this research, and voluntarily sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Have received coronary artery stent surgery or coronary artery bypass graft; 2. Patients with severe lung (respiratory failure), liver (ALT or AST greater than 3 times the normal value and increased bilirubin), kidney (GFR less than 45ml/min/1.73m^2 or dialysis patients) insufficiency; 3. Malignant tumors; 4. Mental illness or intellectual disability; 5. Pregnant or breast-feeding women or those who have family planning; 6. Concomitant diseases that affect calcium balance and soft tissue calcification (hyperparathyroidism, sarcoidosis, amyloidosis); 7. Contra-indications of contrast agents; 8. According to the researcher's judgment, the compliance is poor and the research cannot be completed as required.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| microRNA-32;osteoprotegerin; | — |
Countries
China
Contacts
Public ContactLiu Jianghua
The First Affiliated Hospital of University of South China
Outcome results
None listed