Recurrent abortion of unknown cause
Conditions
Interventions
The experimental group:Take cyclosporine oral solution
The control group:Take placebo
Sponsors
Taizhou People's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 39 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-39 years, spontaneous abortion >= 3 times in the past; 2. Both spouses have no family genetic diseases and have normal chromosomal karyotypes; 3. Both spouses do not smoke; 4. The male semen analysis is normal; 5. The patient himself agrees to participate in this clinical study and signs an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Any infection, endocrine and anatomical abnormalities; 2. Acquire patients with thrombotic hemophilia; 3. The woman is positive for antiphospholipid antibodies or other autoantibodies; 4. Those who have tested positive for TORCH and other infectious diseases; 5. Severe heart, liver, and kidney dysfunction; 6. Those who have been vaccinated 3 months before being selected for the study; 7. Take other experimental drugs within 1 month before being selected for the study or are participating in other clinical studies; 8. Allergic to the taken medicine or its components; 9. The attending doctor believes that it is not suitable to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The opening of the cervix; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood HCG;Blood drug concentration;Autoantibodies;Pathogenic four;Th1;Th2;Th17;Treg;Blood coagulation function;Electrocardiogram; | — |
Countries
China
Contacts
Public ContactGe Hongshan
Taizhou People's Hospital
Outcome results
None listed