Effects of Remazolam Benzylate on a clusterization and weaning-off strategy in elderly patients with respiratory failure: a multicenter prospective randomized controlled study comparing propofol

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100046702

Enrollment

Unknown

Registered

2021-05-27

Start date

2021-06-01

Completion date

Unknown

Last updated

2022-01-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

respiratory failure

Interventions

Group 1:remazolam benzenesulfate

Group 2:propofol

Eligibility

Sex/Gender

All

Age

60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. All meet the diagnostic criteria of respiratory failure in "Modern Respiratory Medicine", the clinical manifestations are dyspnea, cyanosis, severe hypoxemia, blood oxygen partial pressure 28 times/min, requiring mechanical ventilation for >= 48 hours; 2. Aged >= 60 years.

Exclusion criteria

Exclusion criteria: 1. Craniocerebral disease involving the respiratory center and unable to maintain spontaneous breathing rhythm; 2. Patients who suffer from neuromuscular diseases that cause respiratory muscle weakness; 3. Patients with malignant tumors; 4. Patients with end-stage disease.

Design outcomes

Primary

Measure	Time frame
survival and mortality;	—

Secondary

Measure	Time frame
mechanical ventilaatiion time before weaning;the first time of spontaneous breathing test after withdrawal of analgesics;total mechanical ventilation time;time to stay in ICU;the length of hospital stay;	—

Countries

China

Contacts

Public ContactMa Li

Lanzhou University Second Hospital

ery_mali@lzu.edu.cn+86 13893679654

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026