i-PRF/Xenograft composites as grafting materials in endodontic microsurgery with large lesion size

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100046684

Enrollment

Unknown

Registered

2021-05-26

Start date

2021-06-01

Completion date

Unknown

Last updated

2022-03-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periapical periodontitis

Interventions

Experimental Group:i-PRF/Xenograft composites

Control Group:None

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients from 18 to 65 years old who are admitted to the Department of Endodontics and Endodontics, all in good health; 2. Basic periodontal treatment has been completed, which is an indication for apical surgery; 3. And CBCT confirmed that it meets one of the following two conditions: (1) Large-scale apical bone defect (>10mm); (2) Through-and-through lesions. 4. Able to participate in follow-up many times during the study; oral hygiene is good.

Exclusion criteria

Exclusion criteria: 1. Smokers; 2. Pregnant women ; 3. Re-surgery; 4. Unqualified coronal restoration; 5. The teeth with deep periodontal pocket (PD>=5mm); 6. Patients with systemic diseases.

Design outcomes

Primary

Measure	Time frame
Radiopaque Rating Scale;Clinical Examination;Visual analog scale;Cone beam CT;	—

Countries

China

Contacts

Public ContactHan Bing

Peking University Hospital of Stomatology

hanbing822@126.com+86 13811341944

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 12, 2026