Atelectasis
Conditions
Interventions
Experimental group:use a High Flow Heated Respiratory Humidifier for treatment
control group:Standard Oxygen Therapy
Sponsors
The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 65 years; 2. ASA grade 1-3; 3. BMI 18.5-24.9 kg/m2; 4. Underwent elective thoracoscopic pneumonectomy with intraoperative one-lung ventilation (OLV); 5. Agree and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Any lung disease, such as asthma, chronic obstructive pneumonia, lung abscess, recent respiratory infection, etc.; 2. Previous lung surgery history; 3. The surgical site covers the ultrasonic exploration area; 4. Contraindications to HFNC treatment : (1) Insufficient respiratory drive to tolerate intervals of noninvasive ventilation therapy; (2) Acute sinusitis, otitis media; (3) Epistaxis, which may cause gastric inhalation; (4) Certain conditions that may lead to the inhalation of gastric contents; (5) inability to clear respiratory secretions; (6) Hypotension or obvious intravascular hypovolemia; (7) Pneumothorax or mediastinal emphysema; (8) Recent craniocerebral injury or surgery. 5. Inability to tolerate HNFC or COT therapy: Respiratory failure (respiratory rate > 35 times/min,SpO2 120 times/min or more than 30% above the baseline value before treatment; If one or more criteria are met, re-intubation is performed and the patient is converted directly to mechanical ventilation (MV); 6. Any other patient that the Investigator determines is not suitable for this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ultrasound score of nonoperative lung after oxygen therapy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ultrasound score of surgical side lung after oxygen therapy;Arterial carbon dioxide partial pressure;Arterial partial pressure of oxygen;Incidence of significant atelectasis after oxygen therapy;The incidence of hypoxia in the anesthetic resuscitation room;Minimum oxygen saturation in the anesthetic resuscitation room;Duration in anesthesia resuscitation room;length of stay;The incidence of postoperative respiratory events; | — |
Countries
China
Contacts
Public ContactWang Sheng
Anhui Provincial Hospital, Wannan Medical College
Outcome results
None listed