gonitis
Conditions
Interventions
experimental group:Ultrasound-guided IPAK block with intercondylar fossa localization
Sponsors
Subei People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged 65 to 85 years; 2. The ASA classification is I and II; 3. Perform total knee replacement surgery; 4. The subjects (or their legal representatives) have signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Have a history of myocardial infarction or unstable angina pectoris within 6 months before screening, or have a history of serious arrhythmia such as degree II and above atrioventricular block, or a history of NYHA cardiac function classification II and above; 2. Past mental system diseases (such as schizophrenia, depression, etc.) and cognitive dysfunction, or history of epilepsy, Parkinson's syndrome; 3. Subjects who have not received regular antihypertensive treatment or have poor blood pressure control (systolic blood pressure >=160mmHg or =100mmHg or = 11.1mmol/L; 5. Abnormal coagulation function during the screening period: prothrombin time (PT) is prolonged beyond the upper limit of normal by 3 seconds and/or activated partial thromboplastin time (APTT) is prolonged beyond the upper limit of normal by 10 seconds; 6. Taking opioid analgesics continuously for more than 10 days, or the time of taking the last drug is shorter than the 5 half-life of the drug at random.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| a numerical rating scale (NRS) score;Serum C-reactive protein (CRP) and interleukin-6 (IL-6);Bromage score;Quadriceps muscle strength grading;Walking distance; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cumulative use of remedial analgesics;Total number of PCA pump compressions; | — |
Countries
China
Contacts
Public ContactWang Cunjin
Subei People's Hospital
Outcome results
None listed