Gastroesophageal reflux disease
Conditions
Interventions
Sponsors
Yueyang Integrated Traditional Chinese and Western Medicine Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients who meet the diagnostic criteria of laryngopharyngeal reflux (electronic gastroscopy and electronic laryngoscopy within 6 months before enrollment); 2. TCM syndrome differentiation of patients belongs to Qi stagnation and phlegm obstruction; 3. Patients who had not taken acid suppressants or gastrointestinal motility drugs 2 weeks before enrollment; 4. Aged 18 to 70 years, regardless of gender; 5. Patients who understand and agree to participate in this study and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients have one of the following diseases: peptic ulcer, history of gastroesophageal and duodenal surgery, Zollinger-Ellison syndrome, pyloric obstruction, primary esophageal motility disorders (e.g. cardia achalasia, scleroderma, primary esophageal spasm), drug esophagitis, fungal esophagitis, gastrointestinal malignancy; 2. Patients with serious primary diseases of heart, brain, liver, lung, kidney, blood and endocrine system, which have not been effectively controlled, and patients with severe mental illness; 3. Patients who cannot take medication during pregnancy preparation, pregnancy or lactation, and patients who are allergic to the medication used in this study, and patients who cannot cooperate in taking medication and completing related records due to various circumstances; 4. Patients who have participated in or are participating in other clinical trials 2 weeks before enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reflux Symptom Index;Clinical Symptom Score;Reflux Finding Score;Electronic Gastroscopy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Salivary Pepsin;Gastroesophageal Reflux Disease Questionnaire; | — |
Countries
China
Contacts
Public ContactZhou Bingduo
Yueyang Integrated Traditional Chinese and Western Medicine Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed